Date/Time
Date(s) - 09/06/2026
10:00 am - 11:15 am
Categories
Child friendly: No
Ticket Prices:
Telephone Number:
June 9th, 2026 10:00 AM EDT
Session Description
Visualizing the extracellular matrix (ECM) in real-time has long been a challenge. Dr. Kayvon Pedra’s group has developed a novel, cell-impermeant fluorophore that red-shifts and activates upon binding glycans. This allows for seamless, wash-free imaging of glycosylated ECM architecture—from in vitro models to in vivo mouse tumors—providing a powerful new tool for live fluorescence microscopy.
Dr. Kayvon Pedram will introduce a novel red-shifting fluorophore for real-time, wash-free ECM imaging.
Highlights of the presentation
A cell-impermeable small molecule fluorophore turns on and red-shifts upon binding glycosylated biomolecules.
Application of the dye to live biological samples enables wash-free visualization of extracellular matrix structure.
Observations demonstrate no toxicity, a broad substrate profile, deep tissue penetration, and negligible photobleaching in a variety of model organisms.